PALMITOYLATION AND FUNCTION OF GLIAL GLUTAMATE TRANSPORTER-1 IS REDUCED IN THE YAC128 MOUSE MODEL OF HUNTINGTON DISEASE

Palmitoylation and function of glial glutamate transporter-1 is reduced in the YAC128 mouse model of Huntington disease

Excitotoxicity plays a key role in the selective vulnerability of striatal neurons in Huntington disease (HD).Decreased glutamate uptake by glial cells could account for the excess glutamate at the synapse in patients as well as 510 animal models of HD.The major molecule responsible for clearing glutamate at the synapses is glial glutamate transpor

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Opening the digital doorway to sexual healthcare: Recommendations from a behaviour change wheel analysis of barriers and facilitators to seeking online sexual health information and support among underserved populations.

BackgroundThe ability to access and navigate online sexual health information and support is increasingly needed in order to engage with wider sexual healthcare.However, people from underserved 510 populations may struggle to pass though this "digital doorway".Therefore, using a behavioural science approach, we first aimed to identify barriers and

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